The Most Valuable 2021 Panini Score Football Cards

Ranked by real closed-sale prices across 4,787 tracked 2021 Panini Score Football items — not guesses, not asking prices. Updated August 2026; the order shifts as the market does. Right now the crown belongs to Tom Brady [Die Cut] #288 2021 Panini Score Football at $5,000.

On a budget: under $20 · under $50 · under $100

1. 1
   
   Tom Brady [Die Cut] #288 2021 Panini Score Football

   $5,000· $152.53 new/sealed
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2. 2
   
   Tom Brady [Signature Red Zone] #12 2021 Panini Score Football

   $4,850· $4,850 new/sealed
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3. 3
   
   Elijah Moore [Signature End Zone] #337 2021 Panini Score Football

   $849
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4. 4
   
   Mac Jones [Signature Artist's Proof] #306 2021 Panini Score Football

   $432.5
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5. 5
   
   Zach Wilson [Signature Artist's Proof] #304 2021 Panini Score Football

   $300
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6. 6
   
   Josh Allen [Signature Red Zone] #20 2021 Panini Score Football

   $265
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7. 7
   
   Justin Fields [Die Cut] #302 2021 Panini Score Football

   $252.19
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8. 8
   
   Aaron Rodgers [Signature Red Zone] #138 2021 Panini Score Football

   $228.13
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9. 9
   
   Aaron Rodgers [Signature Gold Zone] #138 2021 Panini Score Football

   $216.26
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10. 10
    
    Trevor Lawrence [Signature Artist's Proof] #301 2021 Panini Score Football

    $212.6· $299.99 new/sealed
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11. 11
    
    Trey Lance [Signature First Down] #303 2021 Panini Score Football

    $201.5· $201.5 new/sealed
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12. 12
    
    Justin Fields [Signature First Down] #360 2021 Panini Score Football

    $200
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13. 13
    
    Sony Michel [Signature Gem Master] #38 2021 Panini Score Football

    $199.95
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14. 14
    
    Terry Bradshaw [Signature Red Zone] #120 2021 Panini Score Football

    $180
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15. 15
    
    Deion Sanders [Signature] #55 2021 Panini Score Football

    $177.6
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16. 16
    
    Barry Sanders [Signature Gold Zone] #131 2021 Panini Score Football

    $175· $300 new/sealed
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17. 17
    
    Drew Brees [Signature Gold Zone] #206 2021 Panini Score Football

    $175
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18. 18
    
    Adam Thielen [First Down] #152 2021 Panini Score Football

    $170
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19. 19
    
    Trey Lance [Signature Gold Zone] #303 2021 Panini Score Football

    $165.16· $46.44 new/sealed
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20. 20
    
    Jerry Rice [Signature Red Zone] #276 2021 Panini Score Football

    $165· $165 new/sealed
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21. 21
    
    Jason Kelce [Signature Red Zone] #78 2021 Panini Score Football

    $160
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22. 22
    
    Terry Bradshaw [Signature End Zone] #120 2021 Panini Score Football

    $157.5· $204.99 new/sealed
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23. 23
    
    Ja'Marr Chase [Signature Artist's Proof] #325 2021 Panini Score Football

    $155.23· $102.5 new/sealed
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24. 24
    
    Peyton Manning [Signature Red Zone] #170 2021 Panini Score Football

    $155
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25. 25
    
    Justin Herbert [End Zone] #233 2021 Panini Score Football

    $150
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26. 26
    
    Dan Marino [Signature Gold Zone] #32 2021 Panini Score Football

    $149.99
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27. 27
    
    Jameis Winston [Signature End Zone] #208 2021 Panini Score Football

    $149.95
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28. 28
    
    Christian McCaffrey [Signature Red Zone] #200 2021 Panini Score Football

    $149
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29. 29
    
    John Elway [Signature Gold Zone] #223 2021 Panini Score Football

    $149
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30. 30
    
    Justin Herbert [Signature Gold Zone] #233 2021 Panini Score Football

    $148.38· $341 new/sealed
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31. 31
    
    Randy Moss [Signature Red Zone] #151 2021 Panini Score Football

    $138.11
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32. 32
    
    Ben Roethlisberger [Signature Red Zone] #112 2021 Panini Score Football

    $135
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33. 33
    
    Randy Moss [Signature Gold Zone] #151 2021 Panini Score Football

    $135
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34. 34
    
    Troy Aikman [Signature End Zone] #54 2021 Panini Score Football

    $131.5
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35. 35
    
    Matthew Stafford [Signature Red Zone] #130 2021 Panini Score Football

    $131.28· $278.99 new/sealed
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36. 36
    
    Amon Ra St. Brown [Signature First Down] #330 2021 Panini Score Football

    $127
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37. 37
    
    Christian McCaffrey [Signature End Zone] #200 2021 Panini Score Football

    $124.8
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38. 38
    
    Jason Kelce [Signature] #78 2021 Panini Score Football

    $123.5
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39. 39
    
    Jerry Rice [Signature Gold Zone] #276 2021 Panini Score Football

    $123.05
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40. 40
    
    John Elway [Signature Red Zone] #223 2021 Panini Score Football

    $122.5
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41. 41
    
    Patrick Mahomes II [Signature] #1 2021 Panini Score Football

    $121.01
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42. 42
    
    Jalen Hurts [Signature Gold Zone] #73 2021 Panini Score Football

    $120.28· $430 new/sealed
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43. 43
    
    Drew Brees [Signature Red Zone] #206 2021 Panini Score Football

    $120
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44. 44
    
    Justin Fields [Die Cut] #360 2021 Panini Score Football

    $120
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45. 45
    
    Tom Brady [End Zone] #288 2021 Panini Score Football

    $116.29· $227.5 new/sealed
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46. 46
    
    Justin Fields [Signature End Zone] #360 2021 Panini Score Football

    $115
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47. 47
    
    Jason Kelce [Green] #78 2021 Panini Score Football

    $115
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48. 48
    
    Troy Aikman [Signature Red Zone] #54 2021 Panini Score Football

    $114.5· $225.11 new/sealed
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49. 49
    
    Tom Brady [Gold Zone] #12 2021 Panini Score Football

    $112.5· $52.55 new/sealed
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50. 50
    
    Tom Brady [Signature] #12 2021 Panini Score Football

    $110.61
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Values are informational estimates from real sales data. JunkPal may earn a commission when you buy through eBay links, at no extra cost to you.