The Most Valuable 2021 Panini Donruss Baseball Cards

Ranked by real closed-sale prices across 3,654 tracked 2021 Panini Donruss Baseball items — not guesses, not asking prices. Updated August 2026; the order shifts as the market does. Right now the crown belongs to Luis Garcia [Artist Proof] #45 2021 Panini Donruss Baseball at $295.

On a budget: under $20 · under $50 · under $100

1. 1
   
   Luis Garcia [Artist Proof] #45 2021 Panini Donruss Baseball

   $295
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2. 2
   
   Clayton Kershaw [Mask Emoji] #105 2021 Panini Donruss Baseball

   $200
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3. 3
   
   Mike Trout [Mask Emoji] #14 2021 Panini Donruss Baseball

   $175
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4. 4
   
   Bo Jackson [Press Proof] #213 2021 Panini Donruss Baseball

   $150
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5. 5
   
   Ken Griffey Jr. [SP Variation Artist Proof] #235 2021 Panini Donruss Baseball

   $134.96
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6. 6
   
   Hobby Box 2021 Panini Donruss Baseball

   $130
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7. 7
   
   Aaron Judge [Artist Proof] #2 2021 Panini Donruss Baseball

   $120.28
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8. 8
   
   Ryan Mountcastle [Press Proof] #59 2021 Panini Donruss Baseball

   $120
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9. 9
   
   Babe Ruth [Press Proof] #228 2021 Panini Donruss Baseball

   $111.09· $46.52 new/sealed
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10. 10
    
    Aaron Judge [On Fire] #182 2021 Panini Donruss Baseball

    $108.1· $100 new/sealed
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11. 11
    
    Shohei Ohtani [Press Proof] #199 2021 Panini Donruss Baseball

    $105.3
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12. 12
    
    Steve Garvey [Press Proof] #251 2021 Panini Donruss Baseball

    $100.99
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13. 13
    
    Ichiro [Press Proof] #244 2021 Panini Donruss Baseball

    $85
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14. 14
    
    Aaron Judge [Press Proof] #2 2021 Panini Donruss Baseball

    $79.99
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15. 15
    
    Cello Box 2021 Panini Donruss Baseball

    $76.44
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16. 16
    
    Kyle Lewis [Press Proof] #13 2021 Panini Donruss Baseball

    $75
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17. 17
    
    Ken Griffey Jr. [Press Proof] #235 2021 Panini Donruss Baseball

    $73.13
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18. 18
    
    Retail Box 2021 Panini Donruss Baseball

    $69.99
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19. 19
    
    George Brett [Artist Proof] #221 2021 Panini Donruss Baseball

    $64.43
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20. 20
    
    Aaron Judge [Mask Emoji] #2 2021 Panini Donruss Baseball

    $62· $130.74 new/sealed
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21. 21
    
    Shohei Ohtani [Artist Proof] #199 2021 Panini Donruss Baseball

    $60.5
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22. 22
    
    Ichiro [Mask Emoji] #244 2021 Panini Donruss Baseball

    $60.41
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23. 23
    
    Fernando Tatis Jr. [Artist Proof] #71 2021 Panini Donruss Baseball

    $60· $60 new/sealed
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24. 24
    
    George Brett [Mask Emoji] #221 2021 Panini Donruss Baseball

    $55
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25. 25
    
    Dale Murphy [Press Proof] #255 2021 Panini Donruss Baseball

    $50.5
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26. 26
    
    Ronald Acuna Jr. [Printing Plate] #192 2021 Panini Donruss Baseball

    $50.21
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27. 27
    
    Ryne Sandberg [Press Proof] #245 2021 Panini Donruss Baseball

    $50
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28. 28
    
    Cal Ripken [Press Proof] #234 2021 Panini Donruss Baseball

    $50
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29. 29
    
    George Brett [Press Proof] #221 2021 Panini Donruss Baseball

    $50· $50 new/sealed
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30. 30
    
    Bryce Harper [Press Proof] #18 2021 Panini Donruss Baseball

    $49.99
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31. 31
    
    Mark McGwire [Artist Proof] #262 2021 Panini Donruss Baseball

    $49.99· $49.99 new/sealed
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32. 32
    
    Ken Griffey Jr. [Artist Proof] #235 2021 Panini Donruss Baseball

    $48.1
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33. 33
    
    Dale Murphy [Printing Plate] #255 2021 Panini Donruss Baseball

    $45
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34. 34
    
    Nicholas Castellanos [Mask Emoji] #196 2021 Panini Donruss Baseball

    $44.95
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35. 35
    
    Paul Molitor [Press Proof] #257 2021 Panini Donruss Baseball

    $43· $43 new/sealed
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36. 36
    
    Mike Trout [SP Variation Artist Proof] #170 2021 Panini Donruss Baseball

    $43
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37. 37
    
    Mariano Rivera [Artist Proof] #260 2021 Panini Donruss Baseball

    $40.79
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38. 38
    
    Aaron Judge [SP Variation Season Stat Line] #182 2021 Panini Donruss Baseball

    $40.79
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39. 39
    
    Rafael Palmeiro [Press Proof] #214 2021 Panini Donruss Baseball

    $40
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40. 40
    
    Babe Ruth [Artist Proof] #228 2021 Panini Donruss Baseball

    $40
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41. 41
    
    Bo Bichette [Printing Plate] #165 2021 Panini Donruss Baseball

    $40
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42. 42
    
    Luis Robert [Artist Proof] #143 2021 Panini Donruss Baseball

    $39.99
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43. 43
    
    Fergie Jenkins [Mask Emoji] #230 2021 Panini Donruss Baseball

    $39.99
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44. 44
    
    Orel Hershiser [Press Proof] #224 2021 Panini Donruss Baseball

    $39.95
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45. 45
    
    Mega Box 2021 Panini Donruss Baseball

    $39
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46. 46
    
    Shohei Ohtani [One Hundred] #199 2021 Panini Donruss Baseball

    $36.56· $200 new/sealed
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47. 47
    
    Shohei Ohtani [Presidential Collection] #199 2021 Panini Donruss Baseball

    $35.75· $25.25 new/sealed
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48. 48
    
    Bryce Harper [Mask Emoji] #18 2021 Panini Donruss Baseball

    $35.5
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49. 49
    
    Dale Murphy [Artist Proof] #255 2021 Panini Donruss Baseball

    $35.33
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50. 50
    
    Tyler Stephenson [Mask Emoji] #57 2021 Panini Donruss Baseball

    $35.15
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Values are informational estimates from real sales data. JunkPal may earn a commission when you buy through eBay links, at no extra cost to you.